The 9-1-1 DNA Clamp Is Required for Immunoglobulin Gene Conversion
نویسندگان
چکیده
منابع مشابه
Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion
[This corrects the article DOI: 10.1371/journal.pbio.1000428.].
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DNA-end resection, the generation of single-stranded DNA at DNA double strand break (DSB) ends, is critical for controlling the many cellular responses to breaks. Here we show that the conserved DNA damage checkpoint sliding clamp (the 9-1-1 complex) plays two opposing roles coordinating DSB resection in budding yeast. We show that the major effect of 9-1-1 is to inhibit resection by promoting ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2008
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.00156-08